Interleukin-10 concentration in children undergoing cardiopulmonary bypass
نویسندگان
چکیده
منابع مشابه
Zinc in children undergoing cardiac surgery with cardiopulmonary bypass.
During cardiac surgery with extracorporeal circulation (ECC), a series of immunological and inflammatory alterations occur, which trigger oxidative stress1,2. Under the nonphysiological conditions during the ECC and due to the alterations related to ischemia-reperfusion, a large amount of free radicals is formed3. These are responsible for systemic inflammation and considerable structural and f...
متن کاملGender-related plasma levels of progesterone, interleukin-8 and interleukin-10 during and after cardiopulmonary bypass in infants and children
BACKGROUND It is known that proinflammatory and anti-inflammatory cytokines are released during and after cardiopulmonary bypass (CPB) in infants and children. Sex steroids are known to have immunomodulatory functions, and release of the anti-inflammatory cytokine IL-10 is stimulated by progesterone in vitro. The purpose of the present study was to investigate the plasma levels of progesterone,...
متن کاملThrombin regulation in neonates undergoing cardiopulmonary bypass.
Satu Långström1, Paula Rautiainen2, Leena Mildh2, Kaija Peltola2, Ulla Wartiovaara-Kautto3, Markku Heikinheimo1,4, Jari Petäjä1,5 1Hospital for Children and Adolescents, University of Helsinki, Helsinki, Finland; 2Department of Anesthesia and Intensive Care, Hospital for Children and Adolescents, University of Helsinki, Helsinki, Finland; 3Helsinki University Central Hospital Laboratory Service...
متن کاملInfluence of cardiopulmonary bypass on cefuroxime plasma concentration and pharmacokinetics in patients undergoing coronary surgery.
OBJECTIVES The aims of this study were to evaluate the influence of cardiopulmonary bypass (CPB) on the plasma concentrations and pharmacokinetics of cefuroxime and to assess whether the cefuroxime dose regimen (a 1.5 g dose, followed by 750 mg every 6 h for 24 h) is adequate for cardiac surgery antibiotic prophylaxis. METHODS A prospective, controlled, observational study compared patients u...
متن کاملCerebral oxygenation during cardiopulmonary bypass in children.
OBJECTIVE Previous work has found cerebral oxygen extraction to decrease during hypothermic cardiopulmonary bypass in children. To elucidate cardiopulmonary bypass factors controlling cerebral oxygen extraction, we examined the effect of perfusate temperature, pump flow rate, and hematocrit value on cerebral hemoglobin-oxygen saturation as measured by near infrared spectroscopy. METHODS Forty...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 1996
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(96)70122-8